Eficacia clínica del fosfopéptido de la caseína-fosfato de calcio amorfo. Revisión sistemática

Introducción: La caries dental se ha convertido en un grave problema de salud mundial, por ello hoy día se apuesta por prevención y por los métodos no quirúrgicos para su tratamiento en su fase temprana. El fosfopéptido de la caseína-fosfato de calcio amorfo (CPP-ACP) es uno de los métodos que está en auge actualmente para este fin, y su uso está empezando a extenderse tanto a clínicas dentales como a productos comerciales, sustituyendo en ocasiones al flúor. Objetivo: Evaluar la eficacia del CPP-ACP mediante la realización de una revisión sistemática. Métodología: Se realiza la búsqueda de estudios clínicos in vivo en las bases de datos Pubmed, SCOPUS y Cochrane. Se han incluido todos los trabajos realizados en los últimos 10 años, en humanos y en lengua inglesa y castellana. Se utilizaron las siguientes palabras clave: “Dental caries”, “MI Paste”, “CPP-ACP”, “casein phosphopeptide-amorphous calcium phosphate nanocomplex”, “casein phosphopeptide-amorphous calcium phosphate”. Resultados: Se obtuvieron 20 artículos que cumplían los criterios de inclusión. Conclusión: El tratamiento de la caries incipiente con CPP-ACP es efectivo, sin embargo no existe evidencia científica suficiente para afirmar que sea de más efectividad que el flúor.Introduction: Dental caries has become a serious global health problem, so today the option preferred is prevention and nonsurgical methods for their treatment at early stage. The phosphopeptide casein - amorphous calcium phosphate (CPP- ACP) is a method that is currently booming for this purpose, and its use is beginning to spread both dental clinics as commercial products, replacing sometimes fluoride. Objective: To evaluate the effectiveness of CPP- ACP by conducting a systematic review. Methodology: the search for in vivo clinical studies in PubMed, Scopus and Cochrane data is performed. We included all the work done in the last 10 years, in humans and in English and Spanish. The following keywords were used: “Dental caries”, “MI Paste”, “CPP-ACP”, “casein phosphopeptide-amorphous calcium phosphate nanocomplex”, “casein phosphopeptide-amorphous calcium phosphate”. Results: 20 articles that met the inclusion criteria were obtained. Conclusion: The treatment of incipient caries with CPP- ACP is effective, however there is not enough scientific evidence to say that it is more effective than fluoride.Universidad de Sevilla. Grado en Odontologí

Anàlisi de les defuncions observades i esperades durant l'epidèmia de COVID-19 a Catalunya

Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Defuncions; Mortalitat; Desigualtats en salutCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Defunciones; Mortalidad; Desigualdades en saludCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Deaths; Mortality; Health inequalitiesAquest informe té com a objectiu descriure les defuncions enregistrades per COVID-19 durant l’epidèmia, així com comparar les defuncions observades amb les defuncions esperades per estimar l’excés de defuncions relacionat amb la COVID-19 a Catalunya

Perception of primary health professionals about Female Genital Mutilation : from healthcare to intercultural competence

We are grateful to the INTERDISCIPLINARY GROUP FOR THE PREVENTION AND STUDY OF HARMFUL TRADITIONAL PRACTICES (GIPE/PTP) study group members for their contribution to develop the knowledge about the FGM in Spain. We recommend visiting the group website: http://mgf.uab.esBackground: The practice of Female Genital Mutilation (FGM), a d eeply-rooted tradition in 28 countries in Sub-Saharan Africa, carries important negative consequences for the health and quality of life of women and children. Migratory movements have brought this harmful traditional practice to our medical offices, with the subsequent conflicts related to how to approach this healthcare problem, involving not only a purely healthcare-related event but also questions of an ethical, cultural identity and human rights nature. Methods: The aim of this study was to analyse the perceptions, degree of knowledge, attitudes and practices of the primary healthcare professionals in relation to FGM. A transversal, descriptive study was performed with a self-administered questionnaire to family physicians, paediatricians, nurses, midwives and gynaecologists. Trends towards changes in the two periods studied (2001 and 2004) were analysed. Results: A total of 225 (80%) professionals answered the questionnaire in 2001 and 184 (62%) in 2004. Sixteen percent declared detection of some case in 2004, rising three-fold from the number reported in 2001. Eighteen percent stated that they had no interest in FGM. Less than 40% correctly identified the typology, while less than 30% knew the countries in which the practice is carried out and 82% normally attended patients from these countries. Conclusion: Female genital mutilations are present in primary healthcare medical offices with paediatricians and gynaecologists having the closest contact with the problem. Preventive measures should be designed as should sensitization to promote stands against these practices

Antropomorfo sobre cerámica de la Edad de Hierro de la Meseta

Sin resume

Análisis de la relación volumen-resultado en la cirugía de cáncer digestivo

Cáncer digestivo; Mortalidad intrahospitalaria; Estancia hospitalariaDigestive cancer; Inpatient mortality; Hospital stayCàncer digestiu; Mortalitat intrahospitalària; Estada hospitalàriaL’objectiu general de l’anàlisi és conèixer el número d’intervencions anuals de càncer oncològic digestiu recomanable per centre que afavoreixi els resultats en salut (mortalitat intrahospitalària i reintervencions) i d’eficiència (estada hospitalària) per als pacients intervinguts en el període 2013-2016 als centres que formen part del Sistema Nacional de Salut (SNS).The general objective of this report is to know the number of recommended annual interventions of digestive cancer by center that favor health outcomes (inpatient mortality and reinterventions) and efficiency (hospital stay) for patients who underwent cancer surgery in the period 2013-2016 in the centres belonging to the National Health System (SNS in Spanish).El objeto general del análisis es conocer el número de intervenciones anuales de cáncer oncológico digestivo recomendable por centro que favorezcan los resultados en salud (mortalidad intrahospitalaria y reintervenciones) y de eficiencia (estancia hospitalaria) para los pacientes intervenidos en el periodo 2013-2016 en los centros pertenecientes al Sistema Nacional de Salud (SNS)

Perception of primary health professionals about Female Genital Mutilation: from healthcare to intercultural competence

<p>Abstract</p> <p>Background</p> <p>The practice of Female Genital Mutilation (FGM), a deeply-rooted tradition in 28 countries in Sub-Saharan Africa, carries important negative consequences for the health and quality of life of women and children. Migratory movements have brought this harmful traditional practice to our medical offices, with the subsequent conflicts related to how to approach this healthcare problem, involving not only a purely healthcare-related event but also questions of an ethical, cultural identity and human rights nature.</p> <p>Methods</p> <p>The aim of this study was to analyse the perceptions, degree of knowledge, attitudes and practices of the primary healthcare professionals in relation to FGM. A transversal, descriptive study was performed with a self-administered questionnaire to family physicians, paediatricians, nurses, midwives and gynaecologists. Trends towards changes in the two periods studied (2001 and 2004) were analysed.</p> <p>Results</p> <p>A total of 225 (80%) professionals answered the questionnaire in 2001 and 184 (62%) in 2004. Sixteen percent declared detection of some case in 2004, rising three-fold from the number reported in 2001. Eighteen percent stated that they had no interest in FGM. Less than 40% correctly identified the typology, while less than 30% knew the countries in which the practice is carried out and 82% normally attended patients from these countries.</p> <p>Conclusion</p> <p>Female genital mutilations are present in primary healthcare medical offices with paediatricians and gynaecologists having the closest contact with the problem. Preventive measures should be designed as should sensitization to promote stands against these practices.</p

Atraumatic maxillary sinus elevation using threaded bone dilators for immediate implants. A three-year clinical study

Objective: The aim of this study was to evaluate the efficacy of sinus floor elevation using sequential bone dilators. Materials and Methods: Thirty patients took part in the study (18 women and 12 men) with ages ranging between thirty-six and sixty-three years, selected according to inclusion and exclusion criteria, who showed a bone deficit in the upper posterior alveolar margin of 5-8 mm in height. Sixty expanded platform internal connection implants were placed with diameters of 4/5/4 mm and lengths varying between 10 (n=10) and 11.5 mm (n= 50). Results: Data obtained were analyzed using SPSS 15.0 software. The average intra-sinus bone gain with MP3 biomaterial of porcine origin was 4.13 +/- 0.97 SD mm at the moment of implant placement, 3.90 +/- 1.15 SD mm after twelve months, 3.74 +/- 1.05 SD mm after 24 months and 3.62 +/- 1.75 SD mm after 36 months. Two implants were lost at the moment of prosthesis placement. Conclusions: Alveolar lifting technique in the upper maxilla using bone dilators achieved a 96.6 % implant success rate after a three-year follow-up. Intra-sinus bone biomaterial remodeling was 0.51 +/- 0.08 mm from day zero to the thirty-six-month follow-up. This is a procedure that reduces the amount of surgery necessary and is of both aesthetic and functional benefit to the patient

Perfil dels pacients PADES i utilització que fan dels recursos del sistema sanitari públic català: estudi descriptiu amb dades del món real

Programa d’atenció domiciliària i equips de suport; Atenció sociosanitària; Malaltia crònica complexaHome care program and support equipment; Socio-health care; Complex chronic diseasePrograma de atención domiciliaria y equipos de apoyo; Atención sociosanitaria; Enfermedad crónica complejaAquest document és un estudi descriptiu amb l’objectiu d’analitzar quin és el perfil de pacient del programa PADES i quin és l’ús que fa dels recursos del sistema sanitari públic català, seleccionant una cohort del 2018 i fent un seguiment retrospectiu fins a l’1 de gener de 2017 i un seguiment prospectiu fins al 31 de desembre 2019 per determinar l’ús de recursos.Este documento contiene un estudio descriptivo cuyo objetivo es analizar el perfil del paciente del PADES y el uso que hace de los recursos del sistema sanitario público catalán, seleccionando una cohorte del año 2018 y haciendo un seguimiento retrospectivo hasta el uno de enero de 2017 y un seguimiento prospectivo hasta el 31 de diciembre de 2019 para determinar el uso de los recursos

Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia : a population-based study

To describe and compare demographic and clinical profile of patients newly initiated on aclidinium (ACL) or tiotropium (TIO) and identify factors associated with newly initiated ACL in real-life clinical practice during 2013 in Catalonia. We performed a population-based, retrospective, observational study with data obtained from the Information System for Research Development in Primary Care, a population database that contains information of 5.8 million inhabitants (more than 80% of the Catalan population). Patients over 40 years old, with a recorded diagnosis of COPD and newly initiated treatment with either ACL or TIO during the study period (January to December 2013), were selected. A descriptive analysis of demographic and clinical characteristics was performed, and treatment adherence was also assessed for both cohorts. A total of 8,863 individuals were identified, 4,293 initiated with ACL and 4,570 with TIO. They had a mean age of 69.4 years (standard deviation: 11.3), a median COPD duration of 3 years (interquartile range: 0-8), and 71% were males. Patients treated with ACL were older, with more respiratory comorbidities, a longer time since COPD diagnosis, worse forced expiratory volume in 1 second (% predicted), and with a higher rate of exacerbations during the previous year compared with TIO. It was found that 41.3% of patients with ACL and 62.3% of patients with TIO had no previous COPD treatment. Inhaled corticosteroid and long-acting β2-agonist were the most frequent concomitant medications (32.9% and 32.6%, respectively). Approximately 75% of patients were persistent with ACL or TIO at 3 months from the beginning of treatment, and more than 50% of patients remained persistent at 9 months. Patients initiated with ACL had more severe COPD and were taking more concomitant respiratory medications than patients initiated with TIO. ACL was more frequently initiated as part of triple therapy, while TIO was more frequently initiated as monotherapy

Systematic Review Nanomedicine and Hyperthermia for the Treatment of Gastrointestinal Cancer: A Systematic Review

The incidence of gastrointestinal cancers has increased in recent years. Current treatments present numerous challenges, including drug resistance, non-specificity, and severe side effects, needing the exploration of new therapeutic strategies. One promising avenue is the use of magnetic nanoparticles, which have gained considerable interest due to their ability to generate heat in tumor regions upon the application of an external alternating magnetic field, a process known as hyperthermia. This review conducted a systematic search of in vitro and in vivo studies published in the last decade that employ hyperthermia therapy mediated by magnetic nanoparticles for treating gastrointestinal cancers. After applying various inclusion and exclusion criteria (studies in the last 10 years where hyperthermia using alternative magnetic field is applied), a total of 40 articles were analyzed. The results revealed that iron oxide is the preferred material for magnetism generation in the nanoparticles, and colorectal cancer is the most studied gastrointestinal cancer. Interestingly, novel therapies employing nanoparticles loaded with chemotherapeutic drugs in combination with magnetic hyperthermia demonstrated an excellent antitumor effect. In conclusion, hyperthermia treatments mediated by magnetic nanoparticles appear to be an effective approach for the treatment of gastrointestinal cancers, offering advantages over traditional therapiesPI19/01478 and PMPTA22/00136 (Instituto de Salud Carlos III) (FEDER)Project P20_00540, A-CTS-666-UGR20B-CTS-122-UGR20 and PYC20 RE 035 (Proyectos I + D + i Junta de Andalucía 2020) (FEDER)FP-PRE grant (2021) from the Junta de Andalucia (Spain